Pharmaceutical Development and Technology

This session is of Pharmaceutical technology which is the application of scientific knowledge or technology to pharmacy, pharmacology, and the pharmaceutical industry. It describes techniques, designs, and instrumentation in the preparation, compounding, manufacturing, and packaging, dispensing and accumulating of narcotic and other preparations used in diagnostic and determinative procedures and in the treatment of patients.

This track represents Technology Transfer Pharmaceutical Technology Assessment Quality assurance Bioinformatics and Computational Biology Pharmacological Technology advances Pharmaceutical Packaging and labelling.

• Technology Transfer
• Pharmaceutical Technology Assessment
• Quality assurance
• Bioinformatics and Computational Biology
• Pharmacological Technology advances
• Pharmaceutical Packaging and labelling

For developing a new medicine it will take nearly 10-15 years and on average and costs an average of $2.6 billion. In discovery procedure comprises the initial stages of research, which are intended to recognize an investigational drug and perform primary tests in the lab. This first stage of the process takes   three to six years. By the end, investigators hope to identify a capable drug aspirant to further study in the lab and in animal models, and then in people. These developments offer great ability, but also add complexity to the R&D process. In order to ensure the safety and efficacy of personalized therapies that are used along with diagnostics, clinical trial protocols must be improved and increased.

• Analytical strategies for pharmaceutical products
• Recent trends in Drug Discovery and Development
• Pharmacoeconomics and pharma market research
• Drug Prices and Consumer Value in R&D
• Stability of drugs
• The Audit as a Quality Control Mechanism

The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered (or self-administered) to patients, with the aim to cure them, vaccinate them, or alleviate the symptoms. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.

• Serialization in pharmaceutical industry
• Track and trace in pharma
• GDP Good Distribution Practice
• GMP a legal requirement

Pharmaceutical Sciences combine a wide range of scientific disciplines that are essential to the discovery and development of new drugs and therapies. Pharmaceutical sciences can be classified into the following broad categories, with many specialized areas within each category.

Over the years, pharmaceutical scientists have been instrumental in the discovery and development of innovative drugs that have saved the lives of thousands of people and improved the quality of life for many others. Pharmaceutical scientists can work in a variety of jobs. They are employed by pharmaceutical companies, they work as pharmacists, physicians, researchers and professors at universities, as regulatory scientists for agencies such as the Food and Drug Administration (FDA), and as researchers at national laboratories such as the National Institutes of Health (NIH).

Drug discovery is a process in pharmacy which involves the interaction of various disciplines leading to the invention of potent drug entities. The major part of drug design involves the identification of characteristic diagnostic biomarkers such as a protein responsible for the disease or disorder and then developing a drug molecule of therapeutic potency that targets it. The process involves various branches of pharmacology coalesce with biotechnology, bioinformatics, molecular biology, nanotechnology and biochemistry that ultimately leads to the production of molecules of therapeutic value.

• Diagnostic markers as therapeutic targets
• Approaches in target identification and validation
• In Silicon Structured Based Drug Design
• Drug design and molecular Modelling
• Molecular docking studies

Drug Design Conferences, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and charge to the bimolecular target with which they interact and therefore will bind to it. Drug design frequently but not necessarily relies on computer modelling techniques. This type of modelling is sometimes referred to as computer-aided drug design. Finally, drug design that relies on the knowledge of the three-dimensional structure of the bimolecular target is known as structure-based drug design. In addition to small molecules, biopharmaceuticals and especially therapeutic antibodies are an increasingly important class of drugs and computational methods for improving the affinity, selectivity, and stability of this protein-based therapeutics have also been developed.

• Biomarkers in drug discovery
• Genetics in drug development
• Computer – aided drug design
• Rational drug design approach

Smart drug delivery is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to others. This means of delivery is largely founded on Nano medicine, which plans to employ nanoparticle-mediated drug delivery in order to combat the downfalls of conventional drug delivery. These nanoparticles would be loaded with drugs and targeted to specific parts of the body where there is solely diseased tissue, thereby avoiding interaction with healthy tissue. The goal of targeted drug delivery systems is to prolong, localize, target and have a protected drug interaction with the diseased tissue. The conventional drug delivery system is the absorption of the drug across a biological membrane, whereas the targeted release system releases the drug in a dosage form. The advantages to the targeted release system is the reduction in the frequency of the dosages taken by the patient, having a more uniform effect of the drug, reduction of drug side-effects, and reduced fluctuation in circulating drug levels. The disadvantage of the system is high cost, which makes productivity more difficult and the reduced ability to adjust the dosages.

• Microbial examination of non-sterile products
• Investigating USP sterility testing failure
• Bio burden estimation for medical devices
• Rapid screening methods

Pharmaceutical Analysis is a process or a sequence of processes to identify and/or quantify a substance or drug, the components of a pharmaceutical solution or mixture or the determination of the structures of chemical compounds used in the formulations 2019 of pharmaceutical product. Analytical techniques conferences mainly used for the separation of the components from the mixture and for the determination of the structure of the compounds.

• Health Insurance Portability and Accountability
• Implementing effective compliance policies

Pharmaceutical Chemistry is the study of drug design to optimize pharmacokinetics and pharmacodynamics, and synthesis of new drug molecules. Pharmaceutical Chemistry is a branch of chemistry that deals with the chemical, biochemical and pharmacological aspects of drugs. It includes synthesis/isolation, identification, structural elucidation, structural modification, structural activity relationship (SAR) studies, and study of the chemical characteristics, biochemical changes after drug administration and their pharmacological effects as well as analysis of drugs. In more simple words it is broader than medicinal chemistry in its application also in the fields of analysis, identification, as well as, structural elucidation of drugs.

• Drug discovery & drug development
• Drug targets molecular imaging

Pharmaceutical digital marketing is the use of strategies and technologies to promote products to the right audiences across digital channels. It's an opportunity for pharm brands to leverage cost-effective digital marketing strategies to connect with consumers and healthcare providers.

• Educate audiences with content marketing. Content marketing is the practice of writing, designing, and publishing information online.
• Build a trustworthy brand with reputation management.
• Interact with audiences using social media.
• Increase feedback value with review management.

The drug product manufacturing facility is designed to produce injectable in syringes or vials in Grade an environment. Industries strive to improve product quality in today’s competitive environment and as well reduce the production cost.

• Pre and post gas flushing facility
• Sterile filtration, aseptic filling
• Process development tools
• Stability testing
• Capping, Sealing & Labelling
• Storage and handling of cold-chain products

Pharmacists can play a role helping patients with chronic diseases have better medication at correct time and get good clinical outcomes.  They play a key role in immunization services and identifying vaccine candidates. They Participate and maintain a significant role in multidisciplinary patient care rounds. Patients often make their own decisions about managing their medications. Pharmacists could usefully serve as patient advocates, providing information that permits patients to assess risk and enhance their autonomy.

• Key role in reducing adverse drug events
• Patient counselling
• Communication barriers
• Medical controversies
• Legal and practical aspects of prescribing
• Improving patient care in rural areas
• Reducing healthcare costs
• Improving patient safety

Pharmaceutics encompasses a molecular evaluation of drug metabolism and transport processes and the study of genetic, environmental and disease-related factors that regulate or perturb those processes, as well as the fundamental mathematical relationships between enzyme/transporter function, blood concentration-time profiles and the spectrum of pharmacological effects.

Pharmacotherapeutics is treatment of pathologic conditions through the use of drugs. Pharmacists are specialists in pharmacotherapy and are in charge of guaranteeing the protected, suitable, and prudent utilization of pharmaceutical medications.

• New Chemical Entity
• Pharmaceutical Manufacturing
• Reformulation Considerations
• Pharmaceutical Technology
• Advances in Pharmacodynamics & Pharmacokinetics

Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.