Biography
Biography: Nidhi P. Sapkal
Abstract
Thin films are ideal dosage form for pediatric, geriatric, dysphagic, mentally challenged and bed ridden patients. These films are thin, flat, elegant, rectangular shaped dosage forms that can be delivered by either oral, sublingual or buccal route. In the market, most of the available products are single layered and belong to category of orally dissolving films. A few belong to sublingual and buccal category. The present technology yeilds monolayer films containing single or multiple actives but is not capable of delivering fixed dose combinations that are incompatible with each other. The present investigation describes technology development of thin films consisting of more than one layer. The final product looks like a single thin layer with different colours/shades/textures on both the sides. The method is capable of producing films with two, three or more layers depending upon the need of the product. These films are inseparable from each other during storage, handling and use and importantly, do not interact physically or chemically at the same time. The technology can also be used to deliver actives with different release profiles in thin film form or to deliver single active with different release profiles. This technology can be applied to many buccal or oral care products which require to maintain unidirectional flow of active into a particular direction. Thus, this is an important way to add more attributes to thin film technology.